Cryosurgery has been both effective and predictable in the treatment of benign, premalignant, and superficially malignant oral disease. Its conservative, vital tissue-sparing, nonhemorrhagic, noninfective, painless nature gives it, in our opinion, clear preference over other modes of treatment for oral lesions. The cases presented demonstrate this fact and illustrate cryosurgery's effectiveness as an outpatient surgery technique.