Journal of the American Dental Association, Vol 115, Issue 2, 263-266
Copyright © 1987 by American Dental Association
Efficacy of diphenhydramine hydrochloride for local anesthesia before oral surgery
WJ Gallo
and
E Ellis 3rd
The efficacy of diphenhydramine hydrochloride with epinephrine was tested against lidocaine with epinephrine in a double-blind study. Patients with allergic reactions to general local anesthetics were safely and effectively treated with diphenhydramine hydrochloride as an anesthetic alternative.