The Journal of the American Dental Association
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J Am Dent Assoc, Vol 115, No 2, 263-266.
© 1987 American Dental Association

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Journal of the American Dental Association, Vol 115, Issue 2, 263-266
Copyright © 1987 by American Dental Association


Clinical Trial

Efficacy of diphenhydramine hydrochloride for local anesthesia before oral surgery



WJ Gallo and E Ellis 3rd

The efficacy of diphenhydramine hydrochloride with epinephrine was tested against lidocaine with epinephrine in a double-blind study. Patients with allergic reactions to general local anesthetics were safely and effectively treated with diphenhydramine hydrochloride as an anesthetic alternative.





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