The Journal of the American Dental Association
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J Am Dent Assoc, Vol 122, No 11, 46-48.
© 1991 American Dental Association
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Journal of the American Dental Association, Vol 122, Issue 11, 46-48
Copyright © 1991 by American Dental Association

Journal Article

Saliva and salivary gland alterations in HIV infection



PC Fox
Investigations Section, NIDR, NIH, Bethesda, Md 20892.

HIV-1 infection may involve saliva and the salivary glands. The virus may be recovered from the mouth and anti-viral antibodies are found in saliva. Salivary dysfunction after infection ranges from xerostomia to a Sjogren's syndrome-like condition with persistent glandular enlargement and marked secretory hypofunction.


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R. Crombie, R. L. Silverstein, C. MacLow, S. F. A. Pearce, R. L. Nachman, and J. Laurence
Identification of a CD36-related Thrombospondin 1-binding Domain in HIV-1 Envelope Glycoprotein gp120: Relationship to HIV-1-specific Inhibitory Factors in Human Saliva
J. Exp. Med., January 5, 1998; 187(1): 25 - 35.
[Abstract] [Full Text] [PDF]


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