The Journal of the American Dental Association
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J Am Dent Assoc, Vol 122, No 4, 38-45.
© 1991 American Dental Association
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Journal of the American Dental Association, Vol 122, Issue 4, 38-45
Copyright © 1991 by American Dental Association

Journal Article

Is there a link between fluoridated water and osteosarcoma?



SM McGuire, ED Vanable, MH McGuire, JA Buckwalter, and CW Douglass
Harvard School of Dental Medicine, Boston.

To test the hypothesis that fluoride is a risk factor for osteosarcoma, a case control study compared the complete residential fluoride histories of osteosarcoma patients with matched hospital-based controls. Fluoridation was not found to be a risk factor for osteosarcoma in the study population. The trend in the data from this small sample study suggests the hypothesis that a protective effect may exist against the formation of osteosarcoma for individuals consuming fluoridated water.




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