Journal of the American Dental Association, Vol 123, Issue 11, 61-65
Copyright © 1992 by American Dental Association
Incidence of cleft lips, palates rising
HC Slavkin
Center for Craniofacial Molecular Biology, School of Dentistry, University of Southern California, Los Angeles 90033.
About 1:700 live human births are affected by cleft lip and palate. Socio-economic factors--teenage pregnancies, pregnancies in women older than 35, increased consumption of teratogens during early months of pregnancy--have resulted in increased numbers of congenital malformations in the United States.