The Journal of the American Dental Association
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J Am Dent Assoc, Vol 126, No 1, 74-78.
© 1995 American Dental Association
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RESEARCH

Direct immunofluorescence vs. culture for detecting HSV in oral ulcers: a comparison



LA MacPhail, JF Hilton, GS Heinic and D Greenspan
Department of Stomatology, School of Dentistry, University of California, San Francisco 94143. Diagnostic tests may be necessary to determine the cause of oral ulcers. Direct immunofluorescence staining of oral smears supplies results much more quickly than viral culture, the "gold standard" for diagnosing HSV lesions. This study compares the sensitivity and specificity of direct immunofluorescence staining vs. viral culture and evaluates the usefulness of the two techniques for the general dental practitioner.






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Copyright©1995-1995 American Dental Association (ADA).
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