The Journal of the American Dental Association
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J Am Dent Assoc, Vol 127, No 8, 1202-1213.
© 1996 American Dental Association
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Journal of the American Dental Association, Vol 127, Issue 8, 1202-1213
Copyright © 1996 by American Dental Association

CLINICAL PRACTICE

Recurrent aphthous ulcers: a review of diagnosis and treatment



SB Woo and ST Sonis
Harvard School of Dental Medicine, Boston, USA.

Recurrent aphthous ulcers, or RAU--also called canker sores--are among the oral mucosal conditions that dentists and physicians see most commonly in their patients. Several systemic conditions are associated with oral aphthouslike ulcers, and aphthae themselves often are mistaken for recrudescent oral herpes simplex virus, or HSV, infections. This article will review RAU, describe systemic conditions associated with aphthous-like ulcerations and discuss the differences between RAU and recrudescent oral HSV infections.


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J. M. Jacobson, J. S. Greenspan, J. Spritzler, N. Ketter, J. L. Fahey, J. B. Jackson, L. Fox, M. Chernoff, A. W. Wu, L. A. MacPhail, et al.
Thalidomide for the Treatment of Oral Aphthous Ulcers in Patients with Human Immunodeficiency Virus Infection
N. Engl. J. Med., May 22, 1997; 336(21): 1487 - 1493.
[Abstract] [Full Text] [PDF]


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