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J Am Dent Assoc, Vol 132, No 3, 348-356. © 2001 American Dental Association

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An evidence-based analysis

Background. There are a number of patients and health care professionals who believe dental amalgam restorations are a factor in a host of diseases and conditions. They have been influenced by anecdotal case reports in the medical and dental literature, research published in the refereed literature and media stories concerning the alleged dangers of amalgam restorations.

Methods. The author uses an evidence-based approach in analyzing the data both supporting and condemning the continued use of amalgam restorations. He reviewed the articles from both peer-reviewed and non–peer-reviewed sources and evaluated their relevance, research design and statistical analysis, as well as whether the conclusions follow from the data.

Conclusions. There are numerous logical and methodological errors in the anti-amalgam literature. The author concludes that the evidence supporting the safety of amalgam restorations is compelling.

Clinical Implications. Amalgam restorations remain safe and effective. Dentists should educate patients and other health care professionals who may be mistakenly concerned about amalgam safety.

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				D Lobner and M Asrari Neurotoxicity of Dental Amalgam is Mediated by Zinc J. Dent. Res., March 1, 2003; 82(3): 243 - 246. [Abstract] [Full Text] [PDF]