HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

J Am Dent Assoc, Vol 136, No 12, 1724-1729. © 2005 American Dental Association

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by LAGRAVÈRE, M. O. Articles by FLORES-MIR, C. Search for Related Content PubMed PubMed Citation Articles by LAGRAVÈRE, M. O. Articles by FLORES-MIR, C. Related Collections Esthestics

JADA Continuing Education

A systematic review

Background. The authors conducted a systematic review of the literature to determine the treatment effects of the Invisalign orthodontic system (Align Technology), Santa Clara, Calif.).

Types of Studies Reviewed. The authors reviewed clinical trials that assessed Invisalign’s treatment effects in nongrowing patients. They did not consider trials involving surgical or other simultaneous fixed or removable orthodontic treatment interventions.

Results. The authors searched electronic databases (PubMed, MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, Evidence Based Medicine Reviews, EMBASE Excerpta Medica, Thomsen’s ISI Web of Science and LILACS) with the help of a senior health sciences librarian. They used "Invisalign" as the sole search term, and 22 documents appeared in the combined search. Thereafter, they used "clinical trials," "humans" and "Invisalign treatment effects" as abstract selection criteria. Only two published articles met these inclusion criteria, though after reading the actual articles, the authors determined that they did not adequately evaluate Invisalign treatment effects. Both articles identified methodological issues.

Clinical Implications. The inadequately designed studies the authors found represented only a lower level of evidence (level II). Therefore, the authors found that no strong conclusions could be made regarding the treatment effects of Invisalign appliances. Future prospective randomized clinical trials are required to support, with sound scientific evidence, the claims about Invisalign’s treatment effects. Clinicians will have to rely on their Invisalign clinical experience, the opinions of experts and the limited published evidence when using Invisalign appliances.

Key Words: Invisalign; treatment outcomes; orthodontics

This article has been cited by other articles:

				A. M. Iacopino The Influence of "New Science" on Dental Education: Current Concepts, Trends, and Models for the Future J Dent Educ., April 1, 2007; 71(4): 450 - 462. [Abstract] [Full Text] [PDF]