The Journal of the American Dental Association
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J Am Dent Assoc, Vol 99, No 6, 983-987.
© 1979 American Dental Association
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Journal of the American Dental Association, Vol 99, Issue 6, 983-987
Copyright © 1979 by American Dental Association

Case Reports

Valproic acid: a new antiepileptic drug with potential side effects of dental concern



TM Hassell, GC White 2nd, LG Jewson, and LC Peele 3rd

Although the exact mechanism by which valproic acid acts on hemostasis is unknown, an association between the agent and defective blood clotting and spontaneous hemorrhage is evident. This side effect should be considered in the management of dental patients taking the drug for whom treatment involves surgery of the soft tissues.




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